SCHEMBL8712438

SCHEMBL8712438

CC(=O)NC(Cc1ccc2ccccc2c1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 7/20 0.65
ACE P12821 5/20 0.65
CPA1 P15085 2/20 0.65
ACE2 Q9BYF1 2/20 0.65
TACR1 P25103 1/20 0.64
CA2 P00918 1/20 0.59
PIN1 Q13526 3/20 0.59
MMP9 P14780 2/20 0.54
MMP8 P22894 2/20 0.54
ALB P02768 1/20 0.54
IL2 P60568 1/20 0.54
PTPN1 P18031 1/20 0.53
ACACB O00763 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607215 1.00 MME (0.65) MMEACECPA1ACE2TACR1
SCHEMBL29386502 1.00 MME (0.65) MMEACECPA1ACE2TACR1
SCHEMBL607214 1.00 MME (0.65) MMEACECPA1ACE2TACR1
SCHEMBL29413287 0.92 MME (0.65) MMEACECPA1ACE2TACR1
SCHEMBL23178150 0.88 MME (0.60) MMEACECPA1ACE2TACR1
SCHEMBL30712864 0.88 MME (0.60) MMEACECPA1ACE2TACR1
SCHEMBL30712855 0.88 MME (0.60) MMEACECPA1ACE2TACR1
SCHEMBL15342313 0.88 MME (0.60) MMEACECPA1ACE2TACR1
SCHEMBL29386041 0.88 MME (0.60) MMEACECPA1ACE2TACR1
SCHEMBL22788735 0.87 TACR1 (0.62) MMEACECPA1ACE2TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034192-A1 USE OF GNRH ANTAGONISTS IN MAMMALS TO SYNCHRONIZE FOLLICULAR WAVE EMERGENCE UNIV SASKATCHEWAN (CA) 2026-02-05 US disclosed
EP-4558159-A1 USE OF GNRH ANTAGONISTS IN MAMMALS TO SYNCHRONIZE FOLLICULAR WAVE EMERGENCE University of Saskatchewan (CA) 2025-05-28 EP disclosed
WO-2024016072-A1 USE OF GNRH ANTAGONISTS IN MAMMALS TO SYNCHRONIZE FOLLICULAR WAVE EMERGENCE UNIVERSITY OF SASKATCHEWAN (CA) 2024-01-25 WO disclosed
US-20210094983-A1 MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS NEURO-BIO LTD. (GB) 2021-04-01 US disclosed
CN-102947332-A Novel octapeptide compounds and therapeutic use thereof IPSEN PHARMA SAS 2013-02-27 CN disclosed
US-5767082-A ANTIFERTILITY AGENTS SYNTEX (U.S.A.) INC. (US) 1998-06-16 US disclosed
US-4801577-A REPRODUCTION CONTROL SYNTEX (U.S.A.) INC. (US) 1989-01-31 US disclosed
EP-0097031-B1 NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM SYNTEX (U.S.A.) INC. (US) 1988-09-21 EP disclosed
US-4581169-A Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists SYNTEX (U.S.A.) INC. (US) 1986-04-08 US disclosed
EP-0049628-B1 NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH, USEFUL AS LHRH ANTAGONISTS, METHODS OF MAKING THEM, AND THEIR PHARMACEUTICAL USES SYNTEX (U.S.A.) INC. (US) 1985-07-03 EP disclosed
US-4481190-A LUTEINIZING HORMONE RELEASING HORMONE SYNTEX (U.S.A.) INC. (US) 1984-11-06 US disclosed
EP-0021234-B1 NONAPEPTIDE AND DECAPEPTIDE DERIVATIVES OF LUTEINIZING HORMONE RELEASING HORMONE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYNTEX (U.S.A.) INC. (US) 1984-08-22 EP disclosed
EP-0097031-A2 Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, their preparation and compositions containing them SYNTEX (U.S.A.) INC. (US) 1983-12-28 EP disclosed
US-4419347-A Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists SYNTEX (U.S.A.) INC. (US) 1983-12-06 US disclosed
US-4341767-A Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists SYNTEX INC. (US) 1982-07-27 US disclosed
EP-0049628-A2 Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists, methods of making them, and their pharmaceutical uses SYNTEX (U.S.A.) INC. (US) 1982-04-14 EP disclosed
EP-0021234-A1 Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone, their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1981-01-07 EP disclosed
US-4234571-A CONTRACEPTIVES, ANTIFERTILITY AGENTS SYNTEX (U.S.A.) INC. (US) 1980-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210094983-A1 MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS IAPP, NLN, APP MME 27/4885ACE 1434/4885CPA1 773/4885
US-20260034192-A1 USE OF GNRH ANTAGONISTS IN MAMMALS TO SYNCHRONIZE FOLLICULAR WAVE EMERGENCE GNRHR, FSHR, PGF MME 177/4885ACE 1173/4885CPA1 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.