Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718107 | 0.92 | CLK1 (0.47) | CLK1MAPK9MAPK14HDAC1PSEN1 | |
| SCHEMBL8718412 | 0.83 | PLAU (0.44) | MAPK9MAPK14HDAC1PSEN1PSEN2 | |
| SCHEMBL8715803 | 0.79 | NPC1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8713812 | 0.78 | MAPT (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8714165 | 0.77 | F2 (0.52) | MAPK9MAPK14HDAC1PSEN1PSEN2 | |
| SCHEMBL8715681 | 0.77 | MAPT (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8715687 | 0.77 | CETP (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8904290 | 0.76 | CHRNA7 (0.50) | DHPSCHRNA7KMT2AHTR3ACETP | |
| SCHEMBL8714853 | 0.76 | CHRNA7 (0.50) | DHPSCHRNA7KMT2AHTR3ACETP | |
| SCHEMBL8712595 | 0.76 | MAPT (0.47) | MAPTKMT2ACETPRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |