Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.48 |
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904290 | 1.00 | CHRNA7 (0.50) | CHRNA7UTS2RDHPSRAB9AMEN1 | |
| SCHEMBL8712786 | 0.83 | F10 (0.40) | CHRNA7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8904715 | 0.83 | F10 (0.40) | CHRNA7RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8903628 | 0.81 | DRD2 (0.49) | DRD2DRD4DRD3 | |
| SCHEMBL8713035 | 0.81 | DRD2 (0.49) | DRD2DRD4DRD3 | |
| SCHEMBL8715642 | 0.79 | CETP (0.43) | RAB9ADRD2CETPNPC1ABCB1 | |
| SCHEMBL8904008 | 0.79 | CETP (0.43) | RAB9ADRD2CETPNPC1ABCB1 | |
| SCHEMBL8904014 | 0.79 | DRD2 (0.39) | RAB9ADRD2CETPNPC1ABCB1 | |
| SCHEMBL8903418 | 0.76 | DRD2 (0.38) | RAB9ADRD2CETPNPC1ABCB1 | |
| SCHEMBL8712451 | 0.76 | DHPS (0.45) | CHRNA7DHPSKMT2AHTR3ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |