SCHEMBL8712530

SCHEMBL8712530

O=C(O)c1cccc(SO)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.73
CYP1A2 P05177 1/20 0.73
CYP2C9 P11712 1/20 0.73
HPGD P15428 1/20 0.73
APEX1 P27695 1/20 0.61
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA6 P23280 1/20 0.54
CA9 Q16790 1/20 0.54
KMO O15229 1/20 0.50
UNG P13051 1/20 0.48
DAO P14920 1/20 0.48
TSHR P16473 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
FOLH1 Q04609 2/20 0.47
AKR1C3 P42330 1/20 0.47
TP53 P04637 1/20 0.46
DDB1 Q16531 1/20 0.45
CRBN Q96SW2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2406839 0.84 CYP1A2 (0.76) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL69064 0.84 CYP1A2 (1.00) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL31383422 0.84 CYP1A2 (0.76) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL29380400 0.84 CYP1A2 (1.00) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL24326514 0.81 HPGD (0.48) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL7945686 0.81 CYP1A2 (0.70) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL659462 0.81 HSD17B10 (0.70) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL2801844 0.81 CYP1A2 (0.84) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL16302528 0.81 CYP1A2 (0.70) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL8712966 0.81 HSD17B10 (0.70) HSD17B10CYP1A2CYP2C9HPGDAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-5847061-A Process for producing polymers having terminal functional group which may be protected KURARAY CO., LTD. (JP) 1998-12-08 US disclosed
EP-0704460-B1 PROCESS FOR PRODUCING POLYMER TERMINATED WITH OPTIONALLY PROTECTED FUNCTIONAL GROUP KURARAY CO (JP) 1998-11-04 EP disclosed
EP-0704460-A1 PROCESS FOR PRODUCING POLYMER TERMINATED WITH OPTIONALLY PROTECTED FUNCTIONAL GROUP KURARAY CO., LTD. (JP) 1996-04-03 EP disclosed