SCHEMBL659462

SCHEMBL659462

CSc1cccc(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.70
CYP1A2 P05177 1/20 0.70
CYP2C9 P11712 1/20 0.70
HPGD P15428 1/20 0.70
APEX1 P27695 1/20 0.59
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
POLB P06746 3/20 0.51
MAPT P10636 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
TP53 P04637 1/20 0.51
MAPK1 P28482 1/20 0.51
MCL1 Q07820 2/20 0.50
KDM4E B2RXH2 2/20 0.50
GAA P10253 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664414 1.00 HSD17B10 (0.70) HSD17B10CYP1A2CYP2C9HPGDAPEX1
Iodomethane SCHEMBL6315426 0.96 HSD17B10 (0.66) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL24732325 0.89 KMO (0.61) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL27953642 0.85 ATM (0.52) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL22482430 0.84 L3MBTL1 (0.63) HSD17B10CYP1A2CYP2C9HPGDMEN1
SCHEMBL571165 0.83 MEN1 (0.51) HSD17B10CYP1A2CYP2C9HPGDMEN1
SCHEMBL69064 0.83 CYP1A2 (1.00) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL29380400 0.83 CYP1A2 (1.00) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL2406839 0.83 CYP1A2 (0.76) HSD17B10CYP1A2CYP2C9HPGDAPEX1
SCHEMBL31383422 0.83 CYP1A2 (0.76) HSD17B10CYP1A2CYP2C9HPGDAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-109422547-A A kind of method of zirconia ceramics surface metalation 北京中科华正电气有限公司 2019-03-05 CN claimed
US-20250320204-A1 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC (US) 2025-10-16 US disclosed
US-12414949-B2 Pyrazolyl pyrimidinone compounds and the uses thereof PURDUE RESEARCH FOUNDATION (US) 2025-09-16 US disclosed
US-20250257041-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2025-08-14 US disclosed
EP-4526291-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER The Board of Regents of the University of Texas System (US) 2025-03-26 EP disclosed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN disclosed
WO-2024112123-A1 NOVEL COMPOUND AS SELECTIVE ESTROGEN RECEPTOR MODULATOR 재단법인 대구경북첨단의료산업진흥재단 2024-05-30 WO disclosed
US-20240158372-A1 BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF AMGEN INC. 2024-05-16 US disclosed
WO-2023225327-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-11-23 WO disclosed
CN-111344281-B Potassium channel inhibitors substituted benzimidazoles 阿塞西翁制药公司 2023-11-14 CN disclosed
WO-2000017192-A1 2-ARYLALKYLTHIO -IMIDAZOLES, 2-ARYLALKENYL -THIO -IMIDAZOLES AND 2-ARYLALKINYL -THIO -IMIDAZOLES AS ANTI -INFLAMMATORY SUBSTANCES AND SUBSTANCES INHIBITING THE RELEASE OF CYTOKINE MERCKLE GMBH (DE) 2000-03-30 WO disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-4845088-A ANTIINFLAMMATORY, ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1989-07-04 US disclosed
US-4699904-A ANTIINFLAMMATORY AND ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1987-10-13 US disclosed
EP-0212404-A1 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed
EP-0207447-A2 Tetrazolyl derivatives of beta-lactams useful as elastase inhibitors MERCK & CO. INC. (US) 1987-01-07 EP disclosed
EP-0093484-A2 Antibacterial monic acid derivatives BEECHAM GROUP PLC (GB) 1983-11-09 EP disclosed
US-4014932-A ANTHELMINTICS, PESTICIDES, MITICIDES, INSECTICIDES THE UPJOHN COMPANY (US) 1977-03-29 US disclosed
US-3931318-A ANTHELMINTICS, PESTICIDES THE UPJOHN COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158372-A1 BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF TNNI3, TNNT2, TNNC1 HSD17B10 3855/4885CYP1A2 3774/4885CYP2C9 4026/4885
US-20250257041-A1 INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER DDIT3, ATF4, EIF2AK3 HSD17B10 2778/4885CYP1A2 3619/4885CYP2C9 4377/4885
US-20250320204-A1 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS ENPP1, ENPP3, PDE7A HSD17B10 1416/4885CYP1A2 563/4885CYP2C9 616/4885
US-12414949-B2 Pyrazolyl pyrimidinone compounds and the uses thereof CAP1, ADCY1, ADCYAP1R1 HSD17B10 1917/4885CYP1A2 1092/4885CYP2C9 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.