Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245270 | 0.76 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL7548986 | 0.70 | NPC1 (0.40) | PTPN11 | |
| SCHEMBL5262949 | 0.59 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL4682270 | 0.59 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL257319 | 0.59 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL3275924 | 0.59 | PTPN11 (0.54) | PTPN11 | |
| Hydrochloric Acid SCHEMBL5957709 | 0.58 | PTPN11 (0.52) | PTPN11 | |
| SCHEMBL5654842 | 0.58 | ALDH1A1 (0.47) | PTPN11 | |
| SCHEMBL14944883 | 0.57 | PTPN11 (0.55) | PTPN11 | |
| SCHEMBL8229673 | 0.57 | PTPN11 (0.45) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998041515-A1 | ENDOTHOLIN RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-09-24 | — | — | WO | disclosed |