Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 12/20 | 0.97 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904611 | 0.98 | FDPS (1.00) | FDPSBTN3A1PDE3AGGPS1ALDH1A1 | |
| SCHEMBL8712686 | 0.97 | FDPS (0.97) | FDPSBTN3A1PDE3AGGPS1ALDH1A1 | |
| SCHEMBL11952611 | 0.89 | FDPS (0.82) | FDPSBTN3A1PDE3AGGPS1ALDH1A1 | |
| SCHEMBL8712691 | 0.87 | FDPS (0.79) | FDPSBTN3A1PDE3AGGPS1ALDH1A1 | |
| Water SCHEMBL9226518 | 0.84 | FDPS (0.73) | FDPSBTN3A1PDE3AGGPS1ALDH1A1 | |
| SCHEMBL29459894 | 0.82 | FDPS (0.72) | FDPSALDH1A1KCNA5SMN1; SMN2 | |
| SCHEMBL10622087 | 0.81 | FDPS (0.71) | FDPSALDH1A1SMN1; SMN2 | |
| SCHEMBL8168934 | 0.81 | FDPS (0.69) | FDPSBTN3A1PDE3AGGPS1ALDH1A1 | |
| SCHEMBL8167876 | 0.81 | FDPS (0.69) | FDPSALDH1A1KCNA5SMN1; SMN2 | |
| SCHEMBL9075279 | 0.79 | FDPS (0.68) | FDPSALDH1A1KCNA5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646119-B1 | QUATERNARY NITROGEN-CONTAINING PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM AS WELL AS DENTAL CALCULUS AND PLAQUE | PROCTER & GAMBLE PHARMA (US) | 1998-07-15 | — | — | EP | disclosed |
| EP-0849272-A1 | Quaternary nitrogen-containing phosphonate compounds for treating abnormal calcium and phosphate metabolism as well as dental calculus and plaque | Procter & Gamble Pharmaceuticals, Inc. (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5391743-A | Treating osteoporosis, rheumatoid arthritis, osteoarthritis | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-02-21 | — | — | US | disclosed |