Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | FURIN | P09958 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707560 | 1.00 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4HRH1FFAR4 | |
| SCHEMBL25369234 | 1.00 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4HRH1FFAR4 | |
| SCHEMBL6573174 | 0.89 | NAAA (0.47) | SLC6A2SLC6A3SLC6A4HRH1CHEK2 | |
| SCHEMBL5390747 | 0.89 | NAAA (0.47) | SLC6A2SLC6A3SLC6A4HRH1CHEK2 | |
| SCHEMBL5375027 | 0.89 | NAAA (0.47) | SLC6A2SLC6A3SLC6A4HRH1CHEK2 | |
| SCHEMBL5375025 | 0.89 | NAAA (0.47) | SLC6A2SLC6A3SLC6A4HRH1CHEK2 | |
| SCHEMBL12544887 | 0.88 | HRH1 (0.59) | SLC6A2SLC6A3SLC6A4HRH1FFAR4 | |
| SCHEMBL29856 | 0.80 | HRH1 (0.71) | SLC6A2SLC6A3SLC6A4HRH1EPHX2 | |
| SCHEMBL6575789 | 0.79 | FURIN (0.46) | SLC6A2SLC6A3SLC6A4HRH1FFAR4 | |
| SCHEMBL5383373 | 0.79 | FURIN (0.46) | SLC6A2SLC6A3SLC6A4HRH1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693054-B1 | CYCLOALKYLHYDROXYUREAS AND THEIR USE AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5681858-A | Cycloalkyl hydroxyureas | PFIZER INC. (US) | 1997-10-28 | — | — | US | disclosed |