Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130883 | 0.83 | PTGDR2 (0.71) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5404990 | 0.83 | PTGDR2 (1.00) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5397091 | 0.83 | PTGDR2 (1.00) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4129395 | 0.80 | PTGDR2 (0.70) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL4123938 | 0.80 | PTGDR2 (0.63) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4116335 | 0.79 | PTGDR2 (0.61) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL5497575 | 0.79 | PTGDR2 (0.74) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6977049 | 0.78 | LMNA (0.76) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL5397186 | 0.76 | PTGDR2 (0.67) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4131416 | 0.76 | PTGDR2 (0.71) | PTGDR2LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |