Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712987 | 1.00 | ALOX15 (0.48) | ALOX15ALOX12MMP1PPARAPPARD | |
| SCHEMBL8715549 | 0.88 | SMN1; SMN2 (0.51) | ALOX15ALOX12MMP1PPARASMN1; SMN2 | |
| SCHEMBL8715547 | 0.88 | SMN1; SMN2 (0.51) | ALOX15ALOX12MMP1PPARASMN1; SMN2 | |
| SCHEMBL8717235 | 0.85 | ALOX15 (0.56) | ALOX15ALOX12PPARAPPARDMAPT | |
| SCHEMBL8714097 | 0.85 | ALOX15 (0.52) | ALOX15ALOX12PPARAPPARDSMN1; SMN2 | |
| SCHEMBL8717228 | 0.85 | ALOX15 (0.56) | ALOX15ALOX12PPARAPPARDMAPT | |
| SCHEMBL8714100 | 0.85 | ALOX15 (0.52) | ALOX15ALOX12PPARAPPARDSMN1; SMN2 | |
| SCHEMBL8713917 | 0.84 | ALOX15 (0.51) | ALOX15ALOX12MMP1PPARAPPARD | |
| SCHEMBL8713918 | 0.84 | ALOX15 (0.51) | ALOX15ALOX12MMP1PPARAPPARD | |
| SCHEMBL8713854 | 0.84 | ALOX15 (0.53) | ALOX15ALOX12FOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |