Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713019 | 1.00 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL8818565 | 0.82 | ADORA3 (0.85) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL8818548 | 0.82 | ADORA3 (0.85) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL5391713 | 0.82 | ADORA2A (0.74) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL5390598 | 0.82 | ADORA2A (0.74) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL3436979 | 0.81 | PDE4D (0.66) | ADORA3ADORA2AADORA1ADORA2BRXFP1 | |
| SCHEMBL3436977 | 0.81 | PDE4D (0.66) | ADORA3ADORA2AADORA1ADORA2BRXFP1 | |
| SCHEMBL19959557 | 0.81 | PDE4D (0.66) | ADORA3ADORA2AADORA1ADORA2BRXFP1 | |
| SCHEMBL5394909 | 0.79 | ADORA3 (0.56) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL5392511 | 0.79 | ADORA3 (0.56) | ADORA3ADORA2AADORA1ADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998001459-A1 | NOVEL N-ALKOXYADENINE DERIVATIVES ACTING AS CYTOKINE INHIBITORS | NOVO NORDISK A/S (DK) | 1998-01-15 | — | — | WO | disclosed |