Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715681 | 0.85 | MAPT (0.46) | MAPTSMN1; SMN2KDM4EALDH1A1PSEN1 | |
| SCHEMBL8712543 | 0.84 | MAPT (0.45) | MAPTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8712984 | 0.84 | MAPT (0.44) | MAPTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8904711 | 0.81 | MAPT (0.43) | MAPTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8713959 | 0.77 | IRAK4 (0.40) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8906191 | 0.77 | IRAK4 (0.40) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8715687 | 0.76 | CETP (0.41) | MAPTHPGDPSEN1PSEN2APH1B | |
| SCHEMBL8718107 | 0.74 | CLK1 (0.47) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8719757 | 0.74 | MAPT (0.46) | MAPTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8712602 | 0.73 | HDAC8 (0.40) | MAPTHPGDPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |