Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713959 | 1.00 | IRAK4 (0.40) | IRAK4NPC1RAB9AKMT2ACETP | |
| SCHEMBL8712889 | 0.85 | HPGDS (0.41) | NPC1RAB9AKMT2AHPGDSKDM4E | |
| SCHEMBL8905109 | 0.85 | HPGDS (0.41) | NPC1RAB9AKMT2AHPGDSKDM4E | |
| SCHEMBL8904008 | 0.84 | CETP (0.43) | NPC1RAB9ACETP | |
| SCHEMBL8715642 | 0.84 | CETP (0.43) | NPC1RAB9ACETP | |
| SCHEMBL8904014 | 0.77 | DRD2 (0.39) | IRAK4NPC1RAB9ACETPHPGDS | |
| SCHEMBL8713142 | 0.77 | MAPT (0.46) | NPC1RAB9AKMT2ACETPKDM4E | |
| SCHEMBL8903418 | 0.73 | DRD2 (0.38) | IRAK4NPC1RAB9ACETP | |
| SCHEMBL8903628 | 0.73 | DRD2 (0.49) | — | |
| SCHEMBL8713035 | 0.73 | DRD2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |