Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713179 | 1.00 | GRM4 (0.32) | GRM4TLR7RXRAGRIN1GRIN2B | |
| SCHEMBL8713209 | 0.95 | GRM4 (0.32) | GRM4TLR7RXRAGRIN1GRIN2B | |
| SCHEMBL8710290 | 0.95 | GRM4 (0.32) | GRM4TLR7RXRAGRIN1GRIN2B | |
| SCHEMBL8710286 | 0.95 | GRM4 (0.32) | GRM4TLR7RXRAGRIN1GRIN2B | |
| SCHEMBL8713273 | 0.91 | GRM4 (0.34) | GRM4TLR7RXRAGRIN1GRIN2B | |
| SCHEMBL8713277 | 0.91 | GRM4 (0.34) | GRM4TLR7RXRAGRIN1GRIN2B | |
| SCHEMBL8710242 | 0.91 | GRM4 (0.34) | GRM4TLR7 | |
| SCHEMBL8714262 | 0.91 | GRM4 (0.34) | GRM4TLR7RXRAGRIN1GRIN2B | |
| SCHEMBL8710237 | 0.91 | GRM4 (0.34) | GRM4TLR7 | |
| SCHEMBL8712498 | 0.88 | PDK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716971-A | FOR TREATMENT OF ANGINA PECTORIS AND HYPERTENSION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0623597-B1 | Pyridine derivatives, with potassium channel opening activity | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0623597-A1 | Pyridine derivatives, with potassium channel opening activity | Takeda Chemical Industries, Ltd. (JP) | 1994-11-09 | — | — | EP | disclosed |