Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433452 | 0.85 | TSHR (0.57) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL1507602 | 0.85 | TSHR (0.57) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL28728423 | 0.83 | TSHR (0.67) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL96231 | 0.82 | TSHR (0.64) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL29913891 | 0.80 | VCAM1 (0.64) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL195206 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL3743169 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL1477030 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL27744234 | 0.80 | TSHR (0.61) | TSHRLMNAALDH1A1ACHETDP1 | |
| SCHEMBL57152 | 0.80 | VCAM1 (0.64) | TSHRLMNAALDH1A1ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770586-A | Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism amd methods of treating and preventing dental calculus and plaque | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-23 | — | — | US | disclosed |