Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 6/20 | 0.34 |
| ▸ | CDC25B | P30305 | 6/20 | 0.34 |
| ▸ | CDC25C | P30307 | 5/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22715785 | 0.98 | CDC25A (0.37) | CDC25ACDC25BCDC25CEPHX2CYP1A2 | |
| SCHEMBL6699288 | 0.90 | — | — | |
| SCHEMBL6696319 | 0.88 | — | — | |
| SCHEMBL6703126 | 0.81 | TSHR (0.30) | TSHR | |
| SCHEMBL7098610 | 0.77 | TDP1 (0.31) | EPHX2SCD | |
| SCHEMBL11408447 | 0.74 | CDC25A (0.39) | CDC25ACDC25BCDC25CCYP1A2ALDH1A1 | |
| SCHEMBL28868011 | 0.74 | — | — | |
| SCHEMBL7220404 | 0.64 | CDC25A (0.33) | CDC25ACDC25BCDC25CALDH1A1MAPT | |
| SCHEMBL2494925 | 0.64 | CDC25B (0.33) | CDC25ACDC25BCDC25CALDH1A1MAPT | |
| SCHEMBL7191709 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054162-A1 | PREPARATION OF ALKYL 4,5-DIHYDRO-η,5-DIOXO-2-ARYL-4-OXAZOLEBUTANOATES | FINETECH LTD. (IL) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998054162-A1 | PREPARATION OF ALKYL 4,5-DIHYDRO-η,5-DIOXO-2-ARYL-4-OXAZOLEBUTANOATES | FINETECH LTD. (IL) | 1998-12-03 | — | — | WO | disclosed |
| US-4443461-A | N-[2-[[1-[1H-Indolylalkyl- or oxoalkyl]-4-piperidinyl]-amino]-2-oxoethyl]-arylcarboxamide derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1984-04-17 | — | — | US | disclosed |
| US-4359522-A | Photographic element containing a UV-filter layer | CIBA-GEIGY AG (CH) | 1982-11-16 | — | — | US | disclosed |
| US-4024272-A | Tetracyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-05-17 | — | — | US | disclosed |