SCHEMBL7220404

SCHEMBL7220404

CCCCCC1=NC(CC)(CC)C(=O)O1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 6/20 0.33
CDC25B P30305 6/20 0.33
CDC25C P30307 5/20 0.33
ALOX5 P09917 9/20 0.30
MPEG1 Q2M385 7/20 0.30
XIAP P98170 2/20 0.30
GPR84 Q9NQS5 2/20 0.30
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
PTGES O14684 1/20 0.30
USP2 O75604 1/20 0.30
TP53 P04637 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2494925 0.81 CDC25B (0.33) CDC25ACDC25BCDC25CALOX5MPEG1
SCHEMBL6463410 0.80 CDC25B (0.36) CDC25ACDC25BCDC25CALOX5MPEG1
SCHEMBL1131729 0.74 ACHE (0.39) CDC25BALDH1A1ACHE
SCHEMBL7752907 0.71
SCHEMBL8713406 0.64 CDC25A (0.34) CDC25ACDC25BCDC25CGPR84ALDH1A1
SCHEMBL3484750 0.64 HRH3 (0.32) ALDH1A1
SCHEMBL19383869 0.63 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9526661 0.63 ALDH1A1 (0.38) ALDH1A1
SCHEMBL22715785 0.63 CDC25A (0.37) CDC25ACDC25BCDC25CALDH1A1KMT2A
SCHEMBL10362485 0.63 CDC25A (0.36) CDC25ACDC25BCDC25C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6504046-B1 Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2003-01-07 US disclosed
EP-1092705-A1 PROCESS FOR THE PREPARATION OF AMIDES IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 2001-04-18 EP disclosed