Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19469362 | 0.90 | KMT2A (0.58) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL9098667 | 0.84 | KMT2A (0.51) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL10711121 | 0.84 | SMN1; SMN2 (0.49) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL9509278 | 0.81 | KMT2A (0.47) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL1317710 | 0.81 | KMT2A (0.63) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL29508624 | 0.81 | KMT2A (0.63) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL9244505 | 0.81 | KMT2A (0.54) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL999377 | 0.80 | KMT2A (0.68) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL8014864 | 0.80 | KMT2A (0.68) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL29415231 | 0.80 | ALDH1A1 (0.40) | KMT2AMEN1CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |