SCHEMBL87136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22281315	0.83	KDM4E (0.68)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL14012188	0.80	MAPT (0.60)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL5054851	0.78	MAPT (0.59)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL29634575	0.78	CRHBP (0.52)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL27368087	0.77	KDM4E (0.58)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL3796357	0.77	KDM4E (0.53)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL27654052	0.77	KDM4E (0.50)	KDM4EMAPTALDH1A1HPGDNPC1
	Acrylic Acid SCHEMBL28027777	0.77	KDM4E (0.50)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL22269138	0.77	KDM4E (0.55)	KDM4EMAPTALDH1A1HPGDNPC1
	SCHEMBL15226797	0.76	KDM4E (0.58)	KDM4EMAPTALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.