Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713656 | 1.00 | LMNA (0.47) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8716583 | 0.91 | SLC6A2 (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8716580 | 0.91 | SLC6A2 (0.43) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8716732 | 0.90 | SLC6A2 (0.42) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8716733 | 0.90 | SLC6A2 (0.42) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8719067 | 0.88 | HDAC8 (0.43) | SLC6A2SLC6A4SLC6A3HDAC8CYP2D6 | |
| SCHEMBL8719065 | 0.88 | HDAC8 (0.43) | SLC6A2SLC6A4SLC6A3HDAC8CYP2D6 | |
| SCHEMBL8713650 | 0.86 | SLC6A2 (0.39) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8713648 | 0.86 | SLC6A2 (0.39) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL8718271 | 0.86 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |