Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995960 | 0.80 | HTT (0.45) | HTTBCHEADH1BADH1CADH1A | |
| SCHEMBL13995851 | 0.80 | HTT (0.45) | HTTBCHEADH1BADH1CADH1A | |
| SCHEMBL23967621 | 0.79 | HTT (0.41) | HTTADH1BADH1CADH1AADH4 | |
| SCHEMBL28614835 | 0.78 | HTT (0.33) | HTTADH1BADH1CADH1AADH4 | |
| SCHEMBL9083500 | 0.77 | TSHR (0.39) | HTTADH1BADH1CADH1AADH4 | |
| SCHEMBL14176594 | 0.77 | ADH1B (0.44) | HTTADH1BADH1CADH1AADH4 | |
| SCHEMBL104714 | 0.77 | ADH1B (0.44) | HTTADH1BADH1CADH1AADH4 | |
| SCHEMBL22899465 | 0.77 | ADH1B (0.44) | HTTADH1BADH1CADH1AADH4 | |
| SCHEMBL19432669 | 0.74 | BCHE (0.36) | HTTBCHEADH1BADH1CADH1A | |
| SCHEMBL20144737 | 0.74 | BCHE (0.40) | HTTBCHEADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885880-A2 | Sulfonylalkanoylamino hydroxyethylamino sulfamic acids useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1998-12-23 | — | — | EP | disclosed |