SCHEMBL8714042

SCHEMBL8714042

C=CCN1C2COCC1CC(N)C2

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A4 P31645 1/20 0.34
DRD3 P35462 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8714254 1.00 SLC6A2 (0.34) SLC6A2CHRM1SLC6A4DRD3LMNA
SCHEMBL1573786 0.77 SLC6A2 (0.31) SLC6A2CHRM1SLC6A4DRD3
SCHEMBL8715080 0.76 CYP3A4 (0.34) SLC6A2CHRM1SLC6A4DRD3
SCHEMBL8716615 0.74
SCHEMBL8716612 0.74
SCHEMBL8714421 0.72 ALDH1A1 (0.38) LMNA
SCHEMBL8714425 0.72 ALDH1A1 (0.38) LMNA
SCHEMBL8714412 0.69 CYP2D6 (0.36) LMNA
SCHEMBL8714415 0.69 CYP2D6 (0.36) LMNA
SCHEMBL6632358 0.68 CHRM2 (0.53) SLC6A2DRD3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8169889-A None JP disclosed
EP-0708105-B1 5-HT4 receptor agonists NISSHIN FLOUR MILLING CO (JP) 1998-12-23 EP disclosed
US-5684003-A GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS NISSHIN FLOUR MILLING CO., LTD. (JP) 1997-11-04 US disclosed
JP-H08169889-A 5-HT4 RECEPTOR AGNOSTIC AGENT NISSHIN FLOUR MILLING CO LTD 1996-07-02 JP disclosed
EP-0708105-A1 5-HT4 receptor agonists NISSHIN FLOUR MILLING CO., LTD. (JP) 1996-04-24 EP disclosed