Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.55 |
| ▸ | PNP | P00491 | 2/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.35 |
| ▸ | EP300 | Q09472 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896100 | 0.99 | FGFR1 (0.57) | FGFR1SLC22A6PNPHPRT1EP300 | |
| SCHEMBL4711405 | 0.81 | FGFR1 (0.58) | FGFR1SLC22A6PNPHPRT1EP300 | |
| SCHEMBL8711309 | 0.81 | FGFR1 (0.42) | FGFR1SLC22A6EP300 | |
| SCHEMBL8711315 | 0.78 | FGFR1 (0.46) | FGFR1SLC22A6EP300 | |
| Ammonia Solution, Strong SCHEMBL9126284 | 0.77 | FGFR1 (0.48) | FGFR1SLC22A6PNPHPRT1 | |
| Ammonia Solution, Strong SCHEMBL9126268 | 0.77 | FGFR1 (0.48) | FGFR1SLC22A6PNPHPRT1 | |
| SCHEMBL9569726 | 0.75 | FGFR1 (0.46) | FGFR1SLC22A6EP300 | |
| SCHEMBL9569738 | 0.75 | FGFR1 (0.46) | FGFR1SLC22A6EP300 | |
| SCHEMBL8904777 | 0.75 | FGFR1 (0.52) | FGFR1SLC22A6EP300 | |
| SCHEMBL8845687 | 0.75 | FGFR1 (0.47) | FGFR1SLC22A6PNPEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | claimed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | claimed |
| US-5726174-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-10 | — | — | US | disclosed |
| US-5696265-A | ANTIRETROVIRAL; ANTITUNOR AGENT | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-12-09 | — | — | US | disclosed |
| US-5688778-A | VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-11-18 | — | — | US | disclosed |
| US-5686611-A | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-11-11 | — | — | US | disclosed |
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | disclosed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | disclosed |