SCHEMBL4711405

SCHEMBL4711405

Nc1ccn(CCOCP(=O)(O)O)c(=O)n1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 5/20 0.58
SLC22A6 Q4U2R8 2/20 0.57
TYMP P19971 1/20 0.45
HPRT1 P00492 5/20 0.41
CTSK P43235 1/20 0.39
POLB P06746 2/20 0.38
PNP P00491 1/20 0.38
POLA1 P09884 1/20 0.37
POLG P54098 1/20 0.37
EP300 Q09472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505155 0.88 FGFR1 (0.51) FGFR1SLC22A6HPRT1PNPEP300
SCHEMBL15531740 0.84 POLB (0.56) FGFR1SLC22A6POLBPOLA1POLG
SCHEMBL8896100 0.82 FGFR1 (0.57) FGFR1SLC22A6HPRT1PNPEP300
SCHEMBL8714133 0.81 FGFR1 (0.56) FGFR1SLC22A6HPRT1PNPEP300
SCHEMBL16037312 0.80 FGFR1 (0.50) FGFR1SLC22A6HPRT1POLBPOLA1
SCHEMBL30364353 0.79 FGFR1 (0.46) FGFR1SLC22A6EP300
SCHEMBL20641457 0.78 FGFR1 (0.40) FGFR1SLC22A6EP300
SCHEMBL5802198 0.78 FGFR1 (0.71) FGFR1SLC22A6EP300
SCHEMBL18665283 0.78 FGFR1 (0.41) FGFR1SLC22A6EP300
SCHEMBL20586318 0.76 FGFR1 (0.54) FGFR1SLC22A6EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581714-A1 SYSTEMS AND METHODS FOR AN ADAPTIVE POWER SYSTEM STABILIZER (PSS) General Electric Technology GmbH (CH) 2025-07-09 EP claimed
WO-2025109431-A1 A METHOD FOR DETERMINING A TORQUE DISTRIBUTION BETWEEN A FRONT AXLE AND A REAR AXLE IN A VEHICLE HAVING AN ELECTRIC POWERTRAIN MASERATI S.P.A. (IT) 2025-05-30 WO claimed
CN-119948717-A System and method for adaptive Power System Stabilizer (PSS) 通用电气技术有限公司 2025-05-06 CN claimed
CN-119757880-A Motor dielectric loss testing method considering stator-rotor ditching effect and axial flow 哈尔滨工业大学 2025-04-04 CN claimed
CN-114640279-B Variable frequency motor loss modeling method applicable to energy regulation and control of air-conditioning-like system 广西大学 2025-03-14 CN claimed
US-12197951-B1 Mobile edge computing (MEC) task unloading method with cache mechanism CHENGDU UNIVERSITY OF INFORMATION TECHNOLOGY (CN) 2025-01-14 US claimed
WO-2024091849-A1 SYSTEMS AND METHODS FOR AN ADAPTIVE POWER SYSTEM STABILIZER (PSS) GE INFRASTRUCTURE TECHNOLOGY LLC (US) 2024-05-02 WO claimed
US-20240142926-A1 SYSTEMS AND METHODS FOR AN ADAPTIVE POWER SYSTEM STABILIZER (PSS) GE INFRASTRUCTURE TECHNOLOGY LLC 2024-05-02 US claimed
EP-4305018-A2 SYNTHESIS OF OMECAMTIV MECARBIL Amgen Inc. (US) 2024-01-17 EP claimed
CN-117157274-A Synthesis of olmesartan Mo Kabi mol 安进股份有限公司 2023-12-01 CN claimed
US-11702380-B2 Synthesis of omecamtiv mecarbil AMGEN INC. (US) 2023-07-18 US claimed
CN-110799503-B Synthesis of Meicartine 美国安进公司 2023-06-27 CN claimed
US-20220298099-A1 SYNTHESIS OF OMECAMTIV MECARBIL AMGEN INC. 2022-09-22 US claimed
WO-2022194640-A1 ROTARY ELECTRIC MACHINE VALEO EQUIPEMENTS ELECTRIQUES MOTEUR (FR) 2022-09-22 WO claimed
CN-113449391-B Energy optimal configuration and evaluation method based on thermoelectric coupling 中国航空工业集团公司沈阳飞机设计研究所 2022-09-20 CN claimed
WO-2022192414-A2 SYNTHESIS OF OMECAMTIV MECARBIL AMGEN INC. (US) 2022-09-15 WO claimed
CN-114640279-A Variable frequency motor loss modeling method suitable for energy regulation and control of similar air conditioning system 广西大学 2022-06-17 CN claimed
CN-114520772-A 5G slice resource scheduling method 广州杰赛科技股份有限公司 2022-05-20 CN claimed
CN-114285076-A Virtual inertia configuration method considering dynamic frequency response process 国网青海省电力公司经济技术研究院 2022-04-05 CN claimed
US-6060463-A Treatment of conditions of abnormally increased intraocular pressure by administration of phosphonylmethoxyalkyl nucleoside analogs and related nucleoside analogs Freeman, William (US) 2000-05-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702380-B2 Synthesis of omecamtiv mecarbil SI, MTHFD2, DPYD FGFR1 2016/4885SLC22A6 812/4885TYMP 4/4885
US-20220298099-A1 SYNTHESIS OF OMECAMTIV MECARBIL SI, MTHFD2, DPYD FGFR1 2016/4885SLC22A6 812/4885TYMP 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.