Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713520 | 0.92 | HSD11B1 (0.44) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8712332 | 0.89 | HSD11B1 (0.48) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8712650 | 0.88 | HSD11B1 (0.47) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8717660 | 0.87 | HSD11B1 (0.49) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8715832 | 0.87 | HSD11B1 (0.47) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8712078 | 0.87 | HSD11B1 (0.43) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8711959 | 0.85 | RXFP1 (0.42) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8716384 | 0.84 | HSD11B1 (0.44) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8711620 | 0.84 | HSD11B1 (0.56) | HSD11B1LMNAKMT2ADRD2HTR2A | |
| SCHEMBL8712108 | 0.82 | HSD11B1 (0.45) | HSD11B1LMNAKMT2ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |