Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 9/20 | 0.62 |
| ▸ | HTR3A | P46098 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714748 | 0.95 | HTR4 (0.60) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL8715160 | 0.94 | HTR4 (0.62) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL8713848 | 0.91 | HTR4 (0.74) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8713846 | 0.91 | HTR4 (0.74) | HTR4HTR3ACYP3A4 | |
| SCHEMBL8717880 | 0.87 | HTR4 (0.62) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL8714715 | 0.87 | HTR4 (0.62) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL8717786 | 0.87 | HTR4 (0.62) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL8713864 | 0.87 | HTR4 (0.62) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL8717789 | 0.87 | HTR4 (0.62) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL8714713 | 0.87 | HTR4 (0.62) | HTR4HTR3AALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |