SCHEMBL871426

SCHEMBL871426

CC=CC(=O)OCCC[Si](CC)(CC)OCC

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
HCAR2 Q8TDS4 5/20 0.40
MAPT P10636 2/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
APP P05067 5/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
GSTP1 P09211 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7878186 0.94 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7879596 0.86 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1261771 0.84 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL37109 0.84 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7597935 0.84 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL534802 0.83 TSHR (0.56) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL65272 0.83 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7734220 0.83 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL63718 0.83 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11804106 0.82 ATM (0.48) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5338877-A Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OIL AND FATS CO., LTD. (JP) 1994-08-16 US claimed
EP-4153682-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-06-05 EP disclosed
EP-4153681-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-05-29 EP disclosed
US-11708455-B2 Flame-retardant polycarbonate composition COVESTRO DEUTSCHLAND AG (DE) 2023-07-25 US disclosed
US-20230167296-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2023-06-01 US disclosed
US-20230125361-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2023-04-27 US disclosed
CN-109415556-B Polycarbonate resin composition and molded article thereof 三菱化学株式会社 2021-05-07 CN disclosed
CN-111440275-A Polyorganosiloxane-containing graft copolymer, thermoplastic resin composition, and molded article 三菱化学株式会社 2020-07-24 CN disclosed
CN-111295402-A Rubber-containing graft polymer, resin composition containing rubber-containing graft polymer, and molded article thereof 三菱化学株式会社 2020-06-16 CN disclosed
EP-3168262-B1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TECHNO UMG CO LTD (JP) 2019-09-25 EP disclosed
US-6664362-B2 Blend of aromatic polycarbonate, styrene copolymer, phosphate based flame retardant, wollastonite and controlled chlorine content; moldings with excellent resistance to wet heat and flame retardancy TEIJIN CHEMICALS LTD (JP) 2003-12-16 US disclosed
US-20020151624-A1 Polycarbonate resin composition and molded article TEIJIN CHEMICALS LTD. (JP) 2002-10-17 US disclosed
US-20020147261-A1 Impact-modified polycarbonate compositions BAYER AKTIENGESELLSCHAFT (DE) 2002-10-10 US disclosed
US-6403683-B1 Polycarbonate resin composition and molded article TEIJIN CHEMICALS LTD (JP) 2002-06-11 US disclosed
US-6331373-B1 CHARGE STABILITY AND FLUIDITY NIPPON SHOKUBAI CO., LTD. (JP) 2001-12-18 US disclosed
EP-1026205-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE Teijin Chemicals, Ltd. (JP) 2000-08-09 EP disclosed
EP-0487094-B1 Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OILS & FATS CO LTD (JP) 1996-01-31 EP disclosed
US-5338877-A Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OIL AND FATS CO., LTD. (JP) 1994-08-16 US disclosed
US-5288891-A Reacting an unsaturated silicon compound and a perfluoralkyl peroxide; waterproofing; oil repellents; adhesion; optical lenses; mold release agents NIPPON OIL AND FATS CO. LTD. (JP) 1994-02-22 US disclosed
EP-0487094-A1 Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-05-27 EP disclosed