Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8711598 | 0.99 | CHRNA7 (0.47) | CHRNA7KCNH2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8711956 | 0.99 | CHRNA7 (0.47) | CHRNA7KCNH2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8718227 | 0.99 | CHRNA7 (0.47) | CHRNA7KCNH2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL8712019 | 0.92 | CHRNA7 (0.47) | CHRNA7KCNH2HTR1AHTR7HTR6 | |
| SCHEMBL1794239 | 0.81 | ACSL1 (0.56) | CHRNA7KCNH2MAOAMAOBHRH3 | |
| SCHEMBL1794125 | 0.81 | ACSL1 (0.56) | CHRNA7KCNH2MAOAMAOBHRH3 | |
| SCHEMBL1794127 | 0.81 | ACSL1 (0.56) | CHRNA7KCNH2MAOAMAOBHRH3 | |
| Hydrochloric Acid SCHEMBL8712730 | 0.80 | CHRNA7 (0.46) | CHRNA7KCNH2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3218557 | 0.73 | CHRNA7 (0.58) | CHRNA7 | |
| SCHEMBL3206387 | 0.73 | CHRNA7 (0.58) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |