Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 11/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16943743 | 0.84 | CYP3A4 (0.30) | MAPT | |
| SCHEMBL756061 | 0.80 | PREP (0.33) | LMNA | |
| SCHEMBL16196731 | 0.80 | MKNK1 (0.31) | — | |
| SCHEMBL8905678 | 0.79 | L3MBTL1 (0.34) | L3MBTL1ELANE | |
| SCHEMBL8904505 | 0.79 | L3MBTL1 (0.36) | L3MBTL1ELANEMAPT | |
| SCHEMBL18720685 | 0.77 | L3MBTL1 (0.40) | L3MBTL1ELANEMAPTLMNANPSR1 | |
| SCHEMBL16943742 | 0.75 | ELANE (0.34) | ELANEMAPT | |
| SCHEMBL10520622 | 0.73 | — | — | |
| SCHEMBL4301563 | 0.73 | KMT2A (0.36) | LMNA | |
| SCHEMBL8984541 | 0.73 | MKNK1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | claimed |
| JP-10036259-A | — | — | None | — | — | JP | disclosed |
| JP-H1036259-A | PREVENTIVE AND THERAPEUTIC AGENT FOR CATARACT | KIKKOMAN CORP | 1998-02-10 | — | — | JP | disclosed |
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |