Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411551 | 0.83 | PTGS1 (0.46) | TSHRHPGDCYP2C9MRGPRX4EPAS1 | |
| SCHEMBL27825202 | 0.81 | EPAS1 (0.43) | ALDH1A1HSD11B1EPAS1 | |
| SCHEMBL10930330 | 0.80 | CYP3A4 (0.50) | CYP3A4TSHRALDH1A1ALOX15THRB | |
| SCHEMBL1411728 | 0.80 | CA1 (0.46) | ALDH1A1THRBHPGDCYP2C9CYP2C19 | |
| SCHEMBL12035594 | 0.80 | EPAS1 (0.36) | ADORA2AADORA1MRGPRX4CA2CA1 | |
| SCHEMBL31204254 | 0.80 | CA1 (0.46) | ALDH1A1THRBHPGDCYP2C9CYP2C19 | |
| SCHEMBL6139651 | 0.80 | TSHR (0.41) | TSHRALDH1A1HPGDRECQLHSD11B1 | |
| SCHEMBL8712804 | 0.80 | GAA (0.47) | TSHRALDH1A1HPGDCASP1HSD17B10 | |
| SCHEMBL27370416 | 0.80 | CSNK2A1 (0.49) | HPGDMRGPRX4CA2CA1HTR1A | |
| SCHEMBL1786127 | 0.78 | HSD11B1 (0.44) | HSD11B1MRGPRX4EPAS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750499-A4 | CARBANILIDE ANTICOCCIDIALS | LILLY CO ELI (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0750499-A1 | CARBANILIDE ANTICOCCIDIALS | ELI LILLY AND COMPANY (US) | 1997-01-02 | — | — | EP | disclosed |
| US-5541224-A | ANIMAL FEEDS | ELI LILLY AND COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1995024900-A1 | CARBANILIDE ANTICOCCIDIALS | ELI LILLY AND COMPANY (US) | 1995-09-21 | — | — | WO | disclosed |