Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8711100 | 0.98 | HSD11B1 (0.50) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL8713776 | 0.85 | HSD11B1 (0.45) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL8712047 | 0.80 | HSD11B1 (0.48) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL8711712 | 0.79 | HSD11B1 (0.46) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL8714660 | 0.79 | HSD11B1 (0.53) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL8712265 | 0.79 | HSD11B1 (0.45) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL8712275 | 0.78 | HSD11B1 (0.54) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL8714834 | 0.78 | HSD11B1 (0.46) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| SCHEMBL9232037 | 0.77 | HSD11B1 (0.53) | HSD11B1DRD2HTR2AHTR2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL8715324 | 0.77 | HSD11B1 (0.53) | HSD11B1DRD2HTR2AHTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |