Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 4/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | WNT1 | P04628 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714813 | 0.90 | NPC1 (0.57) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL8714762 | 0.90 | NPC1 (0.57) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL8717794 | 0.88 | NPC1 (0.58) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL9079263 | 0.88 | NPC1 (0.55) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL8713942 | 0.87 | NPC1 (0.61) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL8713946 | 0.87 | NPC1 (0.61) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL8715391 | 0.87 | NPC1 (0.54) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL9077726 | 0.87 | NPC1 (0.54) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL8715388 | 0.87 | NPC1 (0.54) | NPC1RAB9ASMYD3RIPK1HTR3A | |
| SCHEMBL8717883 | 0.87 | NPC1 (0.56) | NPC1RAB9ASMYD3RIPK1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708105-B1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0708105-A1 | 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |