Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704983 | 1.00 | CA2 (0.59) | CA2CA1CA12CA4CA6 | |
| Hydrochloric Acid SCHEMBL8706403 | 0.99 | CA2 (0.58) | CA2CA1CA12CA4CA6 | |
| Hydrochloric Acid SCHEMBL8869995 | 0.92 | CA2 (0.55) | CA2CA1CA12CA4CA6 | |
| SCHEMBL8705889 | 0.89 | CA2 (0.62) | CA2CA1CA12CA4CA6 | |
| Hydrochloric Acid SCHEMBL8709362 | 0.89 | CA2 (0.61) | CA2CA1CA12CA4CA6 | |
| SCHEMBL8710281 | 0.88 | CA2 (0.59) | CA2CA1CA12CA4CA6 | |
| SCHEMBL8705361 | 0.88 | CA2 (0.59) | CA2CA1CA12CA4CA6 | |
| Hydrochloric Acid SCHEMBL8705615 | 0.87 | CA2 (0.58) | CA2CA1CA12CA4CA6 | |
| SCHEMBL9262639 | 0.86 | CA2 (0.44) | CA2CA1CA12CA4CA6 | |
| SCHEMBL8710402 | 0.83 | CA2 (0.65) | CA2CA1CA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625903-B1 | TOPICAL ANTIGLAUCOMA COMPOSITIONS COMPRISING CARBONIC ANHYDRASE INHIBITORS AND BETA-BLOCKERS | ALCON LAB INC (US) | 1998-08-12 | — | — | EP | claimed |