Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242915 | 0.87 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL9249039 | 0.85 | SPHK1 (0.30) | — | |
| SCHEMBL8714481 | 0.84 | SPHK2 (0.34) | ALOX5 | |
| SCHEMBL9243807 | 0.84 | SPHK2 (0.34) | ALOX5 | |
| SCHEMBL9248132 | 0.84 | SPHK2 (0.34) | ALOX5 | |
| SCHEMBL9246777 | 0.83 | — | — | |
| SCHEMBL9567758 | 0.76 | SPHK1 (0.36) | FAAHTRPV1 | |
| SCHEMBL9567753 | 0.76 | SPHK1 (0.36) | FAAHTRPV1 | |
| SCHEMBL9248040 | 0.75 | MEN1 (0.33) | ALOX5FAAH | |
| SCHEMBL8714651 | 0.75 | MEN1 (0.33) | ALOX5FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719291-A | FUNGICIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |