Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456764 | 0.94 | TSHR (0.58) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8519505 | 0.92 | TSHR (0.55) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8714122 | 0.89 | TSHR (0.52) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8712508 | 0.89 | TSHR (0.52) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6361861 | 0.77 | TSHR (0.58) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4747863 | 0.77 | TSHR (0.58) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30172471 | 0.77 | TSHR (0.58) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| Phenylethyl Alcohol SCHEMBL17185910 | 0.75 | TDP1 (0.64) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4448673 | 0.73 | TSHR (0.61) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6930353 | 0.72 | KCNN4 (0.52) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669346-B1 | Solid catalyst components for olefin polymerization and use thereof | NIPPON OIL CO LTD (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0569249-B1 | Ethylene/alpha-olefin copolymers | NIPPON OIL CO LTD (JP) | 1997-08-06 | — | — | EP | disclosed |
| US-5604170-A | EFFECTIVE CATALYST SUPPORT SATISFYING CERTAIN REQUISITES: PARTICLE DIAMETER, SPECIFIC SURFACE AREA, PORE VOLUME, SPECIFIC GRAVITY; SUBJECTED TO ULTRASONIC DISINTEGRATION | NIPPON OIL COMPANY, LIMITED (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0669346-A1 | Solid catalyst components for olefin polymerization and use thereof | NIPPON OIL CO. LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |
| US-5391660-A | Narrow molecular weight distribution by addition polymerizing a olefin or mixtures in a catalysts mixtures having metal compounds, halometal compound and alumoxanes | NIPPON OIL COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0587440-A2 | Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same | NIPPON OIL COMPANY, LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0569249-A2 | Ethylene/alpha-olefin copolymers | NIPPON OIL COMPANY, LIMITED (JP) | 1993-11-10 | — | — | EP | disclosed |