Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128768 | 0.80 | TSHR (0.61) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL21831068 | 0.80 | TSHR (0.61) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL9775748 | 0.79 | TSHR (0.52) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL2761191 | 0.79 | TSHR (0.52) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL456764 | 0.78 | TSHR (0.58) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL6361861 | 0.78 | TSHR (0.58) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL4747863 | 0.78 | TSHR (0.58) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL30172471 | 0.78 | TSHR (0.58) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL151981 | 0.76 | TSHR (0.65) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 | |
| Chlorotriphenylmethane SCHEMBL461 | 0.76 | TSHR (0.65) | TSHRCYP1A2KCNN4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513346-B2 | Flame retardant composition for use in styrenics | CHEMTURA CORPORATION (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120184638-A1 | Flame Retardant Composition for Use in Styrenics | LANXESS SOLUTIONS US INC. | 2012-07-19 | — | — | US | disclosed |
| EP-2115059-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2009-11-11 | — | — | EP | disclosed |
| US-20080306190-A1 | Composition of matter based on alkyl benzyl esters | LANXESS DEUTSCHLAND GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| WO-2008127753-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2008-10-23 | — | — | WO | disclosed |
| EP-1983024-A1 | Material mixture based on alkylbenzyl esters | Lanxess Deutschland GmbH (DE) | 2008-10-22 | — | — | EP | disclosed |
| US-20080221239-A1 | Flame retardant composition for use in styrenics | RECREATIONAL WATER PRODUCTS, INC. | 2008-09-11 | — | — | US | disclosed |
| EP-0023415-A2 | A method of mounting ventilators, lights and the like in sealed relation to an opening and a preformed sealing material for use in such a method | COLT INTERNATIONAL HOLDINGS A.G. (CH) | 1981-02-04 | — | — | EP | disclosed |