Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.55 |
| ▸ | OXTR | P30559 | 2/20 | 0.55 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712963 | 0.88 | AVPR1A (0.69) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8712951 | 0.84 | AVPR2 (0.51) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8712329 | 0.81 | AVPR2 (0.68) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8716136 | 0.81 | AVPR1A (0.47) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8713805 | 0.80 | AVPR2 (0.55) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8716480 | 0.79 | AVPR2 (0.51) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8717630 | 0.79 | AVPR1A (0.57) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8713623 | 0.78 | AVPR2 (0.54) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8713010 | 0.78 | AVPR1A (0.70) | AVPR1AAVPR2OXTRAVPR1BABCB11 | |
| SCHEMBL8712149 | 0.78 | AVPR1A (0.70) | AVPR1AAVPR2OXTRAVPR1BABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |