SCHEMBL8715978

SCHEMBL8715978

COC(C)OC(C)OC(C)C1c2ccccc2-c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
GPR3 P46089 2/20 0.34
CYP1A2 P05177 2/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MAP2K7 O14733 1/20 0.31
GMNN O75496 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CDC25A P30304 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3825829 0.83 POLB (0.40) POLBMEN1KMT2AATMGPR3
SCHEMBL19140921 0.70 CYP1A2 (0.39) POLBMEN1KMT2AATMGPR3
SCHEMBL6675583 0.69 GPR3 (0.46) POLBMEN1KMT2AATMGPR3
SCHEMBL3919889 0.69 GPR3 (0.46) POLBMEN1KMT2AATMGPR3
SCHEMBL25436333 0.69 POLB (0.38) POLBMEN1KMT2AATMGPR3
SCHEMBL431543 0.69 POLB (0.38) POLBMEN1KMT2AATMGPR3
SCHEMBL25412588 0.69 POLB (0.38) POLBMEN1KMT2AATMGPR3
SCHEMBL5933464 0.68 POLB (0.44) POLBMEN1KMT2AATMGPR3
SCHEMBL12237327 0.68 POLB (0.53) POLBKMT2ACYP1A2TSHRALDH1A1
SCHEMBL7597401 0.67 EPHX1 (0.47) POLBMEN1KMT2AATMGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807974-A POLYARYLENEVINYLENE RESIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-09-15 US disclosed