SCHEMBL8716059

SCHEMBL8716059

CCOCC[Si](C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23014926 0.82 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7738612 0.78
SCHEMBL6965978 0.78
SCHEMBL30821611 0.76 TSHR (0.46) ALDH1A1TSHR
SCHEMBL7571343 0.76
SCHEMBL21469750 0.76
SCHEMBL1897932 0.74
SCHEMBL6496407 0.74
SCHEMBL292853 0.73
SCHEMBL1897929 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705659-A Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-01-06 US claimed