Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624886 | 0.93 | RARB (0.50) | RARBS1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9094717 | 0.86 | THRA (0.47) | TP53TSHRPLA2G4B | |
| SCHEMBL9625540 | 0.85 | RARB (0.57) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9624419 | 0.85 | RARB (0.57) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL9624089 | 0.84 | S1PR1 (0.50) | RARBS1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9624597 | 0.83 | S1PR1 (0.48) | RARBS1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9097155 | 0.82 | RARB (0.46) | RARBTP53TSHRPLA2G4A | |
| SCHEMBL9096285 | 0.82 | RARB (0.51) | RARBS1PR1PLA2G4A | |
| SCHEMBL8719683 | 0.82 | RARB (0.52) | RARBS1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9625810 | 0.81 | RARB (0.56) | RARBS1PR1S1PR3TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741438-A | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0395390-B1 | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL CO (JP) | 1994-09-28 | — | — | EP | disclosed |
| EP-0395390-A1 | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |