SCHEMBL8716342

SCHEMBL8716342

CCCCCCC(O)c1ccco1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
TSHR P16473 1/20 0.43
CSNK1E P49674 1/20 0.41
POLB P06746 1/20 0.40
PKM P14618 1/20 0.40
PTPN1 P18031 1/20 0.40
PTPN7 P35236 1/20 0.40
BLM P54132 1/20 0.40
ESR2 Q92731 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GAA P10253 1/20 0.38
HDAC3 O15379 1/20 0.37
GPR84 Q9NQS5 3/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22127720 1.00 KMT2A (0.52) KMT2AMEN1TSHRCSNK1EPOLB
SCHEMBL5613043 1.00 KMT2A (0.52) KMT2AMEN1TSHRCSNK1EPOLB
SCHEMBL20773076 1.00 KMT2A (0.52) KMT2AMEN1TSHRCSNK1EPOLB
SCHEMBL2828919 1.00 KMT2A (0.52) KMT2AMEN1TSHRCSNK1EPOLB
SCHEMBL2139138 0.98 KMT2A (0.50) KMT2AMEN1TSHRCSNK1EPOLB
SCHEMBL7278342 0.92 KMT2A (0.48) KMT2AMEN1TSHRPOLBPKM
SCHEMBL7292793 0.92 KMT2A (0.48) KMT2AMEN1TSHRPOLBPKM
SCHEMBL7292797 0.92 KMT2A (0.48) KMT2AMEN1TSHRPOLBPKM
SCHEMBL10942351 0.86 TSHR (0.47) KMT2AMEN1TSHRPOLBPKM
SCHEMBL27725653 0.85 KMT2A (0.40) KMT2AMEN1TSHRPOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111547749-B Green circulation method for producing ethyl maltol 广东省肇庆华格生物科技有限公司 2023-04-07 CN disclosed
CN-111547749-A Green circulation method for producing ethyl maltol 广东省肇庆华格生物科技有限公司 2020-08-18 CN disclosed
EP-0822936-A1 NOVEL SUBSTITUTED TETRAHYDROPYRANO 3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR ET COMPAGNIE (FR) 1998-02-11 EP disclosed
WO-1996033999-A1 NOVEL SUBSTITUTED TETRAHYDROPYRANO[3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR ET COMPAGNIE (FR) 1996-10-31 WO disclosed
US-4970345-A REARRANGEMENT, HYDROGENATION, DEHYDRATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-13 US disclosed
US-4496767-A REARRANGEMENT, ESTERIFICATION AND REDUCTION OF A FURAN-CARBINOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-01-29 US disclosed