Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 4/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622634 | 1.00 | PTGS1 (0.43) | PTGS1GSTK1GLO1ECE1CTSD | |
| SCHEMBL6831118 | 1.00 | PTGS1 (0.43) | PTGS1GSTK1GLO1ECE1CTSD | |
| SCHEMBL4260374 | 0.99 | PTGS1 (0.44) | PTGS1GSTK1GLO1ECE1CTSD | |
| SCHEMBL8045766 | 0.99 | PTGS1 (0.44) | PTGS1GSTK1GLO1ECE1CTSD | |
| SCHEMBL1472487 | 0.99 | PTGS1 (0.44) | PTGS1GSTK1GLO1ECE1CTSD | |
| SCHEMBL9225749 | 0.97 | PTGS1 (0.44) | PTGS1GSTK1GLO1ECE1CTSD | |
| SCHEMBL8135287 | 0.96 | PTGS1 (0.45) | PTGS1GSTK1GLO1ECE1OPRD1 | |
| SCHEMBL8431345 | 0.96 | PTGS1 (0.45) | PTGS1GSTK1GLO1ECE1OPRD1 | |
| SCHEMBL9067746 | 0.94 | PTGS1 (0.44) | PTGS1GSTK1GLO1ECE1OPRD1 | |
| SCHEMBL1409212 | 0.94 | PTGS1 (0.46) | PTGS1GSTK1GLO1ECE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160289697-A1 | AP2 DOMAIN TRANSCRIPTION FACTOR ODP2 (OVULE DEVELOPMENT PROTEIN 2) AND METHODS OF USE | PIONEER HI BRED INT (US) | 2016-10-06 | — | — | US | disclosed |
| CN-101228279-A | Yield increase in plants overexpressing the MTP genes | BASF PLANT SCIENCE GMBH (DE) | 2008-07-23 | — | — | CN | disclosed |
| CN-1194003-A | Haloperoxidases from curvularia verruculosa and nucleic acids encoding same | NOVO NORDISK AS (DK) | 1998-09-23 | — | — | CN | disclosed |
| EP-0843729-A1 | HALOPEROXIDASES FROM CURVULARIA VERRUCULOSA AND NUCLEIC ACIDS ENCODING SAME | NOVO NORDISK A/S (DK) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997004102-A1 | HALOPEROXIDASES FROM CURVULARIA VERRUCULOSA AND NUCLEIC ACIDS ENCODING SAME | NOVO NORDISK A/S (DK) | 1997-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289697-A1 | AP2 DOMAIN TRANSCRIPTION FACTOR ODP2 (OVULE DEVELOPMENT PROTEIN 2) AND METHODS OF USE | OSBP2, OSBP, OSBPL3 | PTGS1 2332/4885GSTK1 2468/4885GLO1 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.