Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712701 | 0.96 | GPR119 (0.58) | GPR119FAAHRECQLHPGDUSP2 | |
| SCHEMBL7872366 | 0.91 | GPR119 (0.53) | GPR119FAAHRECQLHPGDUSP2 | |
| SCHEMBL15085741 | 0.86 | GPR119 (0.59) | GPR119FAAHRECQLHPGDUSP2 | |
| SCHEMBL7655298 | 0.84 | GPR119 (0.51) | GPR119RECQLHPGDUSP2SMN1; SMN2 | |
| SCHEMBL31597043 | 0.83 | GPR119 (0.61) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL309779 | 0.82 | GPR119 (0.56) | GPR119HPGDKDM4EPKM | |
| SCHEMBL8151168 | 0.82 | GPR119 (0.55) | GPR119FAAHRECQLHPGDUSP2 | |
| SCHEMBL560636 | 0.82 | GPR119 (0.55) | GPR119FAAHRECQLHPGDUSP2 | |
| SCHEMBL2251826 | 0.81 | GPR119 (0.54) | GPR119FAAHRECQLHPGDUSP2 | |
| SCHEMBL1576008 | 0.81 | GPR119 (0.56) | GPR119FAAHRECQLHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |