Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.45 |
| ▸ | HPN | P05981 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719658 | 0.89 | F2 (0.46) | F2HPNST14MMP2MMP9 | |
| SCHEMBL8719964 | 0.89 | F2 (0.59) | F2 | |
| SCHEMBL7294009 | 0.85 | F2 (0.41) | F2HPNST14MMP2MMP9 | |
| SCHEMBL8716561 | 0.76 | F2 (0.61) | F2 | |
| SCHEMBL8717330 | 0.76 | F2 (0.61) | F2 | |
| SCHEMBL7299062 | 0.74 | F2 (0.43) | F2HPNST14MMP2MMP9 | |
| SCHEMBL7294015 | 0.73 | MMP2 (0.39) | F2HPNST14MMP2MMP9 | |
| SCHEMBL8947654 | 0.73 | F2 (0.55) | F2 | |
| SCHEMBL8716988 | 0.72 | F2 (0.58) | F2 | |
| SCHEMBL7303156 | 0.70 | F2 (0.38) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |