Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10058949 | 0.92 | RAB9A (0.59) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10058957 | 0.92 | RAB9A (0.59) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10058970 | 0.92 | RAB9A (0.59) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10058950 | 0.92 | RAB9A (0.59) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10058952 | 0.92 | RAB9A (0.59) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10058947 | 0.90 | RAB9A (0.61) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15164266 | 0.87 | KDM4E (0.68) | ALDH1A1RAB9AKDM4ETP53MAPT | |
| SCHEMBL15164267 | 0.86 | RAB9A (0.54) | ALDH1A1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9702885 | 0.86 | KDM4E (0.66) | ALDH1A1RAB9AKDM4ETP53MAPT | |
| SCHEMBL9704102 | 0.84 | RAB9A (0.60) | ALDH1A1RAB9AKDM4ETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847149-A | Thiadiazole derivatives, process for their preparation, and their use as precursors for the production of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |