Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8714261 | 0.95 | PTGIR (0.51) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| Fumaric Acid SCHEMBL8714256 | 0.95 | PTGIR (0.51) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL8711220 | 0.92 | PTGIR (0.56) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL8710939 | 0.91 | HSD11B1 (0.52) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL8711336 | 0.89 | PTGIR (0.55) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL8712161 | 0.88 | CYP2C9 (0.58) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL8711249 | 0.88 | PTGIR (0.54) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL8716637 | 0.88 | PTGIR (0.54) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| Fumaric Acid SCHEMBL8715314 | 0.87 | PTGIR (0.54) | PTGIROPRM1ALDH1A1LMNAHSD11B1 | |
| Fumaric Acid SCHEMBL8716585 | 0.86 | HSD11B1 (0.47) | PTGIROPRM1HSD11B1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |