SCHEMBL8716781

SCHEMBL8716781

CCCCCO[C@H]1CO[C@H]2[C@@H]1OC[C@H]2O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 0.46
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.42
BCHE P06276 4/20 0.42
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PPP5C P53041 1/20 0.36
SPHK2 Q9NRA0 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18107571 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18107969 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18107569 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18108269 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18108272 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18118480 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18107572 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18107973 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL1896686 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE
SCHEMBL18107970 0.98 GBA1 (0.49) GBA1THRBLMNAMAPTBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5837669-A CLEANING COMPOUNDS FOR HAIR OR BODIES CECA S.A. (FR) 1998-11-17 US disclosed