Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL575606 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL778185 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL19347772 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL778819 | 0.75 | TSHR (0.46) | SMN1; SMN2 | |
| SCHEMBL778817 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL779200 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL777014 | 0.72 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL8716784 | 0.69 | — | — | |
| SCHEMBL9558843 | 0.68 | TSHR (0.32) | SMN1; SMN2 | |
| SCHEMBL575493 | 0.67 | TSHR (0.52) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537996-B1 | Avermectin compounds with a 6,5-spiroketal ring system and a 23-acyl substituent | MERCK & CO INC (US) | 1998-01-07 | — | — | EP | disclosed |