Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622094 | 0.84 | TP53 (0.60) | MAPTRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL6981476 | 0.83 | MAPT (0.50) | MAPTTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3721459 | 0.81 | LMNA (0.59) | MAPTRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL28107976 | 0.79 | MAPT (0.77) | MAPTCASP3SENP7TDP1ALPG | |
| SCHEMBL5101629 | 0.79 | LMNA (0.51) | MAPTCASP3SENP7TDP1RAB9A | |
| SCHEMBL980266 | 0.78 | TNKS (0.56) | RAB9ANPC1POLBSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL23420320 | 0.77 | TP53 (0.46) | MAPTRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL30686654 | 0.77 | TP53 (0.46) | MAPTRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL3726748 | 0.77 | TP53 (0.46) | MAPTRAB9ANPC1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29695992 | 0.77 | TP53 (0.46) | MAPTRAB9ANPC1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739350-A | COMPOUNDS CAPABLE OF BEING LINKED TO MONOCLONAL ANTIBODIES FOR DELIVERY TO TARGET CELLS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-14 | — | — | US | disclosed |