Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20976187 | 0.84 | GAA (0.53) | MEN1KMT2AOPRM1LMNASIGMAR1 | |
| SCHEMBL4632546 | 0.84 | GAA (0.53) | MEN1KMT2AOPRM1LMNASIGMAR1 | |
| SCHEMBL8720326 | 0.84 | HRH3 (0.44) | MEN1KMT2ACHRM2NPSR1DRD3 | |
| Hydrochloric Acid SCHEMBL4169355 | 0.83 | GAA (0.52) | MEN1KMT2AOPRM1LMNA | |
| SCHEMBL14354524 | 0.76 | CHRM2 (0.56) | CYP2B6MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL6425483 | 0.76 | KCNA3 (0.44) | OPRM1CYP2D6KDM4EKCNA3 | |
| SCHEMBL8267456 | 0.75 | SLC6A2 (0.50) | ATMCYP2D6LMNASIGMAR1SLC6A2 | |
| SCHEMBL13099830 | 0.74 | CYP2B6 (0.47) | CYP2B6MEN1KMT2AATMCHRM2 | |
| SCHEMBL12073029 | 0.73 | CHRM2 (0.51) | CYP2B6MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL8570755 | 0.73 | CHRM2 (0.66) | MEN1KMT2ACHRM2CHRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |